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| Nomenclature |
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Symbol:
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Lrp1tm2Her
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Name:
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low density lipoprotein receptor-related protein 1;
targeted mutation 2, Joachim Herz
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MGI ID: |
MGI:2180880 |
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Synonyms: |
LRPflox, lrplox |
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Gene:
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Lrp1
Location:
Chr10:127538161-127621148 bp, - strand
Genetic Position: Chr10,
74.52 cM, cytoband B2-D1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:76281
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Parent Cell Line:
| JH1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A loxP-flanked PGK-neomycin selection cassette was inserted 240 bp upstream of the transcription initiation site, and a third loxP site was inserted 3' to exon 2 in intron 2. (J:76281)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:76281
Rohlmann A et al.,
"Sustained somatic gene inactivation by viral transfer of Cre recombinase."
Nat Biotechnol 1996 Nov;14(11):1562-5
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All: |
37 reference(s)
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Analysis Tools
