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| Nomenclature |
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Symbol:
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Tg(Ckmm-Cav3)1Ysu
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Name:
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transgene insertion 1, Yoshihide Sunada
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MGI ID: |
MGI:2180562 |
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Synonyms: |
CAV-3P104L, TgCAV3M1 |
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Transgene:
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Tg(Ckmm-Cav3)1Ysu
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/Slc x DBA/Slc)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Sequence encoding Cav3 modified to contain proline to leucine missense mutation at codon 104 was adjoined to a 6.5-kb fragment of the Ckmm promoter region. Expression of the transgene and endogenous Cav3 gene were confirmed by Northern blot and RT-PCR analyses, respectively. (J:67174)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:67174
Sunada Y et al.,
"Transgenic mice expressing mutant caveolin-3 show severe myopathy associated with increased nNOS activity."
Hum Mol Genet 2001 Feb 1;10(3):173-8
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All: |
5 reference(s)
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Analysis Tools
