|
|
| Nomenclature |
|
Symbol:
|
Tlx3tm1Sjk
|
|
Name:
|
T cell leukemia, homeobox 3;
targeted mutation 1, Stanley J Korsmeyer
|
|
MGI ID: |
MGI:2180105 |
|
Synonyms: |
Rnx-, Tlx3- |
|
Gene:
|
Tlx3
Location:
Chr11:33200752-33203588 bp, - strand
Genetic Position: Chr11,
19.21 cM, cytoband A5
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:60751
|
|
Parent Cell Line:
| RW-4 (ES Cell) |
|
Strain of Origin:
|
129X1/SvJ
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A PGK-neo cassette was inserted into exon 1. RNA in situ analysis confirmed the lack of gene expression in homozygous mice. (J:60751)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Tlx3 Mutation:
|
4 strains or lines available |
|
| References |
|
Original: |
J:60751
Shirasawa S et al.,
"Rnx deficiency results in congenital central hypoventilation."
Nat Genet 2000 Mar;24(3):287-90
|
|
All: |
11 reference(s)
|
|
Analysis Tools
