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| Nomenclature |
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Symbol:
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Acadvltm1Uab
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Name:
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acyl-Coenzyme A dehydrogenase, very long chain;
targeted mutation 1, University of Alabama
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MGI ID: |
MGI:2180080 |
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Synonyms: |
VLCAD- |
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Gene:
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Acadvl
Location:
Chr11:70010183-70015411 bp, - strand
Genetic Position: Chr11,
42.96 cM, cytoband B2-B5
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:72193
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette was used to replace exons 7 through 19 and the first 33 nucleotides of exon 20. Western analysis of the livers of homozygous mutant mice showed an absence of protein. (J:72193)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:72193
Cox KB et al.,
"Gestational, pathologic and biochemical differences between very long-chain acyl-CoA dehydrogenase deficiency and long-chain acyl-CoA dehydrogenase deficiency in the mouse."
Hum Mol Genet 2001 Sep 15;10(19):2069-77
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All: |
7 reference(s)
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Analysis Tools
