|
|
| Nomenclature |
|
Symbol:
|
Ptger2tm1Brey
|
|
Name:
|
prostaglandin E receptor 2 (subtype EP2);
targeted mutation 1, Richard M Breyer
|
|
MGI ID: |
MGI:2179967 |
|
Synonyms: |
EP2- |
|
Gene:
|
Ptger2
Location:
Chr14:44988195-45003820 bp, + strand
Genetic Position: Chr14,
22.68 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:53646
|
|
Parent Cell Line:
| TL1/TL-1 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A PGK-neomycin resistance cassette replaced part of the amino terminal coding sequence, including 420 bp from the ATG start codon to codon 140. (J:53646)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:53646
Kennedy CR et al.,
"Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor."
Nat Med 1999 Feb;5(2):217-20
|
|
All: |
31 reference(s)
|
|
Analysis Tools
