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| Nomenclature |
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Symbol:
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F2rl1tm1Cgh
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Name:
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coagulation factor II (thrombin) receptor-like 1;
targeted mutation 1, Shaun R Coughlin
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MGI ID: |
MGI:2179844 |
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Synonyms: |
F2rl1tm1Kley, PAR-2-, PAR2- |
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Gene:
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F2rl1
Location:
Chr13:95511732-95525240 bp, - strand
Genetic Position: Chr13,
49.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:76626
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Parent Cell Line:
| RF8 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 was replaced with a neomycin resistance cassette via homologous recombination. Homozygous mutant animals were identified by Southern blot analysis. (J:76626)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:76626
Lindner JR et al.,
"Delayed onset of inflammation in protease-activated receptor-2-deficient mice."
J Immunol 2000 Dec 1;165(11):6504-10
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All: |
18 reference(s)
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Analysis Tools
