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| Nomenclature |
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Symbol:
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Acvr2atm1Hsch
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Name:
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activin receptor IIA;
targeted mutation 1,Heinrich Schrewe
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MGI ID: |
MGI:2179547 |
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Synonyms: |
AcrRIIA-, Acvr2atm1Enl, IIA-, IIA-KO |
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Gene:
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Acvr2a
Location:
Chr2:48814109-48903269 bp, + strand
Genetic Position: Chr2,
28.38 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:57262
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The kinase domain of this gene was disrupted by replacing 135 bp of exon 9 and 1.3 kb of intron 9 with a neo cassette by homologous recombination. Homozygous mutant animals were identified by Southern blot analysis. (J:57262)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Acvr2a Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:57262
Song J et al.,
"The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice."
Dev Biol 1999 Sep 1;213(1):157-69
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All: |
8 reference(s)
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Analysis Tools
