|
|
| Nomenclature |
|
Symbol:
|
Cfc1tm1Mms
|
|
Name:
|
cripto, FRL-1, cryptic family 1;
targeted mutation 1, Michael M Shen
|
|
MGI ID: |
MGI:2179530 |
|
Synonyms: |
Cryptic |
|
Gene:
|
Cfc1
Location:
Chr1:34535648-34544311 bp, + strand
Genetic Position: Chr1,
13.34 cM, cytoband B
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:58104
|
|
Parent Cell Line:
| TC1/TC-1 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: Most of exon 3 and all of exons 4 and 5 were replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant E7.5 embryos were identified by PCR analysis. (J:58104)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Cfc1 Mutation:
|
9 strains or lines available |
|
| References |
|
Original: |
J:58104
Yan YT et al.,
"Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation."
Genes Dev 1999 Oct 1;13(19):2527-37
|
|
All: |
6 reference(s)
|
|
Analysis Tools
