|
|
| Nomenclature |
|
Symbol:
|
Slit2tm1Matl
|
|
Name:
|
slit homolog 2 (Drosophila);
targeted mutation 1, Marc Tessier-Lavigne
|
|
MGI ID: |
MGI:2179460 |
|
Synonyms: |
Slit2- |
|
Gene:
|
Slit2
Location:
Chr5:47983155-48306282 bp, + strand
Genetic Position: Chr5,
26.05 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:73904
|
|
Parent Cell Line:
| D3 (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: Insertion of a floxed PGK-neomycin resistance cassette preceded by an inframe stop codon, an IRES element, and sequences encoding a tauGFP fusion protein, deleted part of two 5' exons including the putative signal sequence (SS) and sequences encoding part of the first leucine rich repeat. (J:73904)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:73904
Plump AS et al.,
"Slit1 and Slit2 cooperate to prevent premature midline crossing of retinal axons in the mouse visual system."
Neuron 2002 Jan 17;33(2):219-32
|
|
All: |
33 reference(s)
|
|
Analysis Tools
