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| Nomenclature |
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Symbol:
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Tbx1tm1Bem
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Name:
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T-box 1;
targeted mutation 1, Bernice Morrow
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MGI ID: |
MGI:2179191 |
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Synonyms: |
Tbx1-, Tbx1tm1Rak |
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Gene:
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Tbx1
Location:
Chr16:18581713-18586969 bp, - strand
Genetic Position: Chr16,
11.51 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:67796
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Parent Cell Line:
| WW6 (ES Cell) |
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Strain of Origin:
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STOCK 129/Sv and C57BL/6J and SJL
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A genomic fragment containing exons 1 and 2 was replaced with a hygromycin resistance cassette. (J:67796)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tbx1 Mutation:
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10 strains or lines available |
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| References |
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Original: |
J:67796
Merscher S et al.,
"TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome."
Cell 2001 Feb 23;104(4):619-29
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All: |
13 reference(s)
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Analysis Tools
