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| Nomenclature |
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Symbol:
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Tg(Camk2a-tTA)1Mmay
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Name:
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transgene insertion 1, Mark Mayford
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MGI ID: |
MGI:2179066 |
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Synonyms: |
CamDAT, CaMKIIalpha-tTA, CaMKII-tTA, CAMK-rTA, line B, pCaMKII-tTA, Tgalpha-CaMkII-tTA, Tg(CaMKIItTA)Mmay |
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Transgene:
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Tg(Camk2a-tTA)1Mmay
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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Not Specified
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The transgene contains the tetracycline-controlled transactivator protein (tTA) under regulatory control of the forebrain specific calcium/calmodulin-dependent kinase II promoter. (J:37107)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
This transgene is line B. Transgenic mice are viable, fertile, and display no overt phenotypic defects. Administration of tetracycline analogs such as doxycycline blocks transgene expression.
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| References |
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Original: |
J:37107
Mayford M et al.,
"Control of memory formation through regulated expression of a CaMKII transgene."
Science 1996 Dec 6;274(5293):1678-83
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All: |
121 reference(s)
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Analysis Tools
