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| Nomenclature |
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Symbol:
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Sycp3tm1Hoog
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Name:
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synaptonemal complex protein 3;
targeted mutation 1, Christer Hoog
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MGI ID: |
MGI:2179041 |
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Synonyms: |
SCP3- |
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Gene:
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Sycp3
Location:
Chr10:88459569-88473236 bp, + strand
Genetic Position: Chr10,
43.94 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:60153
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 1-3 were replaced with a neomycin cassette via homologous recombination. Gene transcripts and protein were absent in testes of adult homozygous mutant animals as assayed by Northern and Western blot, respectively. (J:60153)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Sycp3 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:60153
Yuan L et al.,
"The murine SCP3 gene is required for synaptonemal complex assembly, chromosome synapsis, and male fertility."
Mol Cell 2000 Jan;5(1):73-83
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All: |
21 reference(s)
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Analysis Tools
