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| Nomenclature |
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Symbol:
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Cebpetm1Kgx
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Name:
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CCAAT/enhancer binding protein (C/EBP), epsilon;
targeted mutation 1, Kleanthis G Xanthopoulos
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MGI ID: |
MGI:2178607 |
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Synonyms: |
C/EBPepsilon- |
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Gene:
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Cebpe
Location:
Chr14:54710363-54712174 bp, - strand
Genetic Position: Chr14,
27.9 cM
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Cebpetm1Kgx/Cebpetm1Kgx mice exhibit a variety of lesions associated with opportunistic bacetrial infections
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:76024
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 1.2 kb genomic fragment containing 334 bp of sequence encoding the bZIP region was replaced with a neomycin selection cassette. Northern blot analysis on RNA derived from bone marrow cells demonstrated that no detectable transcript was expressed from this allele. (J:76024)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cebpe Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:76024
Yamanaka R et al.,
"Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice."
Proc Natl Acad Sci U S A 1997 Nov 25;94(24):13187-92
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All: |
11 reference(s)
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Analysis Tools
