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| Nomenclature |
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Symbol:
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Clec3btm1Umw
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Name:
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C-type lectin domain family 3, member b;
targeted mutation 1, Ulla M Wewer
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MGI ID: |
MGI:2178555 |
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Synonyms: |
Tet -, Tnatm1Umw |
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Gene:
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Clec3b
Location:
Chr9:123150946-123157430 bp, + strand
Genetic Position: Chr9,
73.91 cM, cytoband F1-F3
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:72638
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The transcription start site and exon 1 (which contains the translation start site) were replaced by a neo cassette. RT-PCR and Northern blot analyses demonstrated absence of transcript from several tissues in homozygous mutant mice. Western blotting verified absence of protein from serum in mutant mice. (J:72638)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Clec3b Mutation:
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1 strain or line available |
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| References |
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Original: |
J:72638
Iba K et al.,
"Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity."
Mol Cell Biol 2001 Nov;21(22):7817-25
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All: |
2 reference(s)
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