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| Nomenclature |
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Symbol:
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Smarcad1tm1Gos
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Name:
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SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1;
targeted mutation 1, Achim Gossler
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MGI ID: |
MGI:2177964 |
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Synonyms: |
Etl1leo, Etl1TgN(6LSN)3Gos |
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Gene:
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Smarcad1
Location:
Chr6:65042667-65116049 bp, + strand
Genetic Position: Chr6,
30.11 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:56661
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: A lacZ-neomycin fusion gene was inserted in-frame immediately downstream of the initiation codon. Western blot analysis on doubly targeted ES cells confirmed that no ETL1 protein was expressed from this allele; however, beta-galactosidase was expressed under the control of the endogenous promoter. (J:56661)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Smarcad1 Mutation:
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170 strains or lines available |
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| References |
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Original: |
J:56661
Schoor M et al.,
"Skeletal dysplasias, growth retardation, reduced postnatal survival, and impaired fertility in mice lacking the SNF2/SWI2 family member ETL1."
Mech Dev 1999 Jul;85(1-2):73-83
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All: |
1 reference(s)
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Analysis Tools
