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| Nomenclature |
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Symbol:
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Tg(KRT14-cre)8Brn
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Name:
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transgene insertion 8, Anton Berns
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MGI ID: |
MGI:2177243 |
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Synonyms: |
K14cre, K14-Cre, Tg(KRT14-cre)1Brn |
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Transgene:
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Tg(KRT14-cre)8Brn
Location:
unknown
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Histological and Immunochemical examinaton of skin and teeth of Apctm2Rak/Apctm2Rak Tg(KRT14-cre)8Brn/0 mice at P12
Show the 10 image(s) involving this allele.
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses Cre recombinase under the control of a human keratin 14 promoter. This promoter is active in skin, salivary gland and mammary gland epithelium. Mammary gland epithelium recombination efficiency was estimated at a weak 5-30%. (J:73028)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:73028
Jonkers J et al.,
"Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer."
Nat Genet 2001 Dec;29(4):418-25
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All: |
52 reference(s)
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Analysis Tools
