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| Nomenclature |
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Symbol:
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Waptm1(cre)Arge
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Name:
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whey acidic protein;
targeted mutation 1, Argiris Efstratiadis
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MGI ID: |
MGI:2177210 |
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Synonyms: |
Wapcre |
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Gene:
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Wap
Location:
Chr11:6635482-6638637 bp, - strand
Genetic Position: Chr11,
4.61 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:70564
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Parent Cell Line:
| W9.5/W95 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A cre gene followed by a neomycin selection cassette was inserted into the 5' noncoding region of the gene. Activity assays demonstrated that Cre recombinase activity was detectable in mammary gland of heterozygous and homozygous mice. (J:70564)
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Recombinase activity
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Driver:
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Wap
Summary of all recombinase alleles
driven by Wap.
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MGI has not yet included tissue activity data for this allele in any anatomical systems.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Wap Mutation:
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27 strains or lines available |
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| References |
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Original: |
J:70564
Ludwig T et al.,
"Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice."
Oncogene 2001 Jul 5;20(30):3937-48
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All: |
5 reference(s)
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Analysis Tools
