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| Nomenclature |
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Symbol:
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Bcl2l1tm1.1Mam
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Name:
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BCL2-like 1;
targeted mutation 1.1, Lothar Hennighausen
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MGI ID: |
MGI:2176700 |
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Synonyms: |
Bcl-xf, fl |
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Gene:
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Bcl2l1
Location:
Chr2:152780668-152831728 bp, - strand
Genetic Position: Chr2,
75.41 cM, cytoband H1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:63161
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: This allele is a derivative of Bcl2ltm1Mam in which the loxP flanked neomycin cassette was removed in the germline by mating mice carrying this allele to Tg(EIIa-Cre)1Lmgd mice. A single loxP site remains in place of the loxP flanked selection cassette and a second loxP site is located 3' to exon 2 in the final allele. (J:63161)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:63161
Rucker EB 3rd et al.,
"Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis"
Mol Endocrinol 2000 Jul;14(7):1038-52
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All: |
21 reference(s)
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Analysis Tools
