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| Nomenclature |
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Symbol:
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Tg(CAG-cat-lacZ)11Miya
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Name:
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transgene insertion 11, Jun-ichi Miyazaki
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MGI ID: |
MGI:2176512 |
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Synonyms: |
CAG-CAT-Z, CAG-CAT-Z11, loxP-LlacZ, Tg(ACTB-cat-lacZ)11Miya |
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Transgene:
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Tg(CAG-cat-lacZ)11Miya
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: This allele is used to detect transient expression of Cre recombinase. The transgene carries a lacZ gene downstream of a CMV enhancer and chicken beta-actin promoter and a floxed chloramphenicol acetyltransferase gene (a stuffer sequence). Upon Cre-mediated excision of the stuffer sequence, the modified allele expresses lacZ in tissues where Cre is expressed. The authors state that a single copy of the transgene was inserted and expression was observed throughout all embryonic and adult stages. (J:69322)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
The authors state that the strain of origin is "BDF1."
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| References |
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Original: |
J:69322
Sakai K et al.,
"A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission."
Biochem Biophys Res Commun 1997 Aug 18;237(2):318-24
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All: |
45 reference(s)
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Analysis Tools
