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| Nomenclature |
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Symbol:
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Il4tm1Kopf
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Name:
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interleukin 4;
targeted mutation 1, Manfred Kopf
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MGI ID: |
MGI:2176268 |
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Synonyms: |
IL-4-, IL-4null |
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Gene:
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Il4
Location:
Chr11:53602982-53618669 bp, - strand
Genetic Position: Chr11,
31.97 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:14593
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
| |
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A neomycin resistance cassette was inserted into the third exon of the gene. (J:14593)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:14593
Kopf M et al.,
"Disruption of the murine IL-4 gene blocks Th2 cytokine responses."
Nature 1993 Mar 18;362(6417):245-8
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All: |
56 reference(s)
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Analysis Tools
