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| Nomenclature |
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Symbol:
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Smotm2Amc
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Name:
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smoothened homolog (Drosophila);
targeted mutation 2, Andrew P McMahon
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MGI ID: |
MGI:2176256 |
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Synonyms: |
Smoc, Smof, Smofl, Smoflox |
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Gene:
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Smo
Location:
Chr6:29735694-29761365 bp, + strand
Genetic Position: Chr6,
12.36 cM, cytoband A3.3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:73071
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Parent Cell Line:
| AV3 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: Two loxP sites flank ~400 bp of exon 1 from 44 bp upstream through 358 bp downstream of the translation initiation codon and an frt-flanked neomycin resistance sequence. (J:73071)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:73071
Long F et al.,
"Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation."
Development 2001 Dec;128(24):5099-108
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All: |
72 reference(s)
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Analysis Tools
