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| Nomenclature |
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Symbol:
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Smotm1Amc
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Name:
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smoothened homolog (Drosophila);
targeted mutation 1, Andrew P McMahon
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MGI ID: |
MGI:2176255 |
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Synonyms: |
Smo-, Smon, Smonull, Smorec |
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Gene:
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Smo
Location:
Chr6:29735694-29761365 bp, + strand
Genetic Position: Chr6,
12.36 cM, cytoband A3.3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:175111
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Parent Cell Line:
| AV3 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An frt-flanked neomycin resistance cassette replaced a segment containing 44 bp upstream and 358 bp downstream of the translation initiation codon. (J:175111)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:175111
Zhang XM et al.,
"Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node."
Cell 2001 Jul 27;106(2):781-92
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All: |
47 reference(s)
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Analysis Tools
