Tg(CMV-cre)1Cgn
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(CMV-cre)1Cgn
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Name:
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transgene insertion 1, University of Cologne
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MGI ID: |
MGI:2176180 |
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Synonyms: |
CMV-Cre, CMV:Cre, Cre deleter, DCre, deleter, TgN(CMV-Cre)#Cgn, ubi-cre |
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Transgene:
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Tg(CMV-cre)1Cgn
Location:
unknown
Genetic Position: ChrX,
Syntenic
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Transgene
origin |
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Strain of Origin:
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BALB/cJ
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses Cre recombinase under the control of a human cytomegalovirus (CMV) promoter, active in most cells and tissues. (J:75204)
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Recombinase activity
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Activity in:
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adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
early embryo,
embryo-other,
endocrine system,
hemolymphoid system,
integumental system,
liver & biliary system,
muscle,
nervous system,
renal & urinary system,
respiratory system
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Driver:
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CMV
Summary of all recombinase alleles
driven by CMV.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Homozygous transgenic mice are viable and fertile. The transgene appears to be X-linked since transgene transmission through males is restricted to female offspring.
In transgenic mice, in conjunction with a transgene carrying a loxP-flanked gene, deletion of the loxP-flanked gene occurs in all tissues including germ cells.
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| References |
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Original: |
J:75204
Schwenk F et al.,
"A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells."
Nucleic Acids Res 1995 Dec 25;23(24):5080-1
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All: |
394 reference(s)
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Analysis Tools
