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| Nomenclature |
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Symbol:
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Meox2tm1(cre)Sor
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Name:
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mesenchyme homeobox 2;
targeted mutation 1, Philippe Soriano
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MGI ID: |
MGI:2176174 |
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Synonyms: |
Meox2Cre, Meox2-Cre, Meox2CreSor, MORE, More-cre, Mox2Cre, Mox2 Cre, Mox2-Cre |
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Gene:
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Meox2
Location:
Chr12:37108540-37181785 bp, + strand
Genetic Position: Chr12,
16.84 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:60933
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Parent Cell Line:
| AK7 (ES Cell) |
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Strain of Origin:
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129S4/SvJaeSor
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: An nls-cre gene was inserted at the initiator ATG of the gene, followed by a neomycin selection cassette. The endogenous regulatory sequences drive expression by E5 in the epiblast and by E7 expression is detectable in all primitive ectoderm but not endoderm or trophectoderm. (J:60933, J:105278, J:132360)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:60933
Tallquist MD et al.,
"Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function."
Genesis 2000 Feb;26(2):113-5
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All: |
178 reference(s)
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Analysis Tools
