Tg(MMTV-cre)4Mam
Transgene Detail
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| Nomenclature |
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Symbol:
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Tg(MMTV-cre)4Mam
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Name:
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transgene insertion 4, Lothar Hennighausen
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MGI ID: |
MGI:2176166 |
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Synonyms: |
CreD, D-line, Line D, MMTV-Cre, MMTV-CreD, MMTV-CreNLST |
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Transgene:
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Tg(MMTV-cre)4Mam
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene directs the expression of Cre recombinase under the control of the mouse mammary tumor virus (MMTV) long terminal repeat. The viral MMTV promoter directed expression of Cre recombinase in the secretory epithelium of the mammary gland, the salivary gland, seminal vesicle, skin, erythrocytes, B and T cells. This line does not express cre in oocytes. (J:67925, J:74366)
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Recombinase activity
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Activity in:
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alimentary system,
cardiovascular system,
embryo-other,
endocrine system,
hemolymphoid system,
integumental system,
liver & biliary system,
nervous system,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs
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Not detected in:
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adipose tissue,
cavities & their linings,
extraembryonic component,
limbs,
mesenchyme,
muscle,
skeletal system,
tail
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Driver:
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MMTV
Summary of all recombinase alleles
driven by MMTV.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
This transgene is the D line. Line A (1) was also produced.
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| References |
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Original: |
J:67925
Wagner KU et al.,
"Cre-mediated gene deletion in the mammary gland."
Nucleic Acids Res 1997 Nov 1;25(21):4323-30
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All: |
77 reference(s)
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Analysis Tools
