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| Nomenclature |
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Symbol:
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Tg(Syn1-cre)671Jxm
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Name:
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transgene insertion 671, Jamey Marth
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MGI ID: |
MGI:2176055 |
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Synonyms: |
cresyn1, Syn-cre, SynI-Cre |
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Transgene:
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Tg(Syn1-cre)671Jxm
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x CBA)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: This transgene expresses Cre recombinase under the control of a rat synapsin I promoter. Cre recombinase activity is detected in neuronal cells, including brain, spinal cord and DRGs, as early as E12.5, as well as in neurons in adult. (J:68558)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Homozygous transgenic mice are viable, fertile, normal in size, and do not display any gross physical or behavioral abnormalities.
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| References |
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Original: |
J:68558
Zhu Y et al.,
"Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain."
Genes Dev 2001 Apr 1;15(7):859-76
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All: |
54 reference(s)
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Analysis Tools
