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| Nomenclature |
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Symbol:
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Nr0b1tm1.1Lja
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Name:
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nuclear receptor subfamily 0, group B, member 1;
targeted mutation 1.1, J Larry Jameson
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MGI ID: |
MGI:2159321 |
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Synonyms: |
Ahchdelta2, Dax1-, Dax1KO |
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Gene:
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Nr0b1
Location:
ChrX:86191764-86195947 bp, + strand
Genetic Position: ChrX,
39.67 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:51292
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: This allele is a derivative of Nr0b1tm1Lja in which Cre-mediated recombination in vivo under control of a CMV promoter excised exon 2 in the germline. RT-PCR analyses of pituitary, adrenal glands, and gonads did not detect full length transcript in either homozygous female mice or hemizygous male mice. (J:51292)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:51292
Yu RN et al.,
"Role of Ahch in gonadal development and gametogenesis [see comments]"
Nat Genet 1998 Dec;20(4):353-7
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All: |
16 reference(s)
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Analysis Tools
