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| Nomenclature |
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Symbol:
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Man2a2tm1Mfu
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Name:
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mannosidase 2, alpha 2;
targeted mutation 1, Michiko N Fukuda
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MGI ID: |
MGI:2158829 |
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Synonyms: |
MX- |
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Gene:
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Man2a2
Location:
Chr7:80349098-80371375 bp, - strand
Genetic Position: Chr7,
45.65 cM, cytoband D2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:73658
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced exon 2, which contains the translation initiation site. Western blot analysis using polyclonal antibodies did not detect protein in testes from homozygous mutant mice. (J:73658)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Man2a2 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:73658
Akama TO et al.,
"Germ cell survival through carbohydrate-mediated interaction with Sertoli cells."
Science 2002 Jan 4;295(5552):124-7
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All: |
3 reference(s)
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Analysis Tools
