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| Nomenclature |
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Symbol:
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Npy1rtm1Tped
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Name:
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neuropeptide Y receptor Y1;
targeted mutation 1, Thierry Pedrazzini
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MGI ID: |
MGI:2158699 |
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Synonyms: |
NPY-, Npyr1-, Y1- |
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Gene:
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Npy1r
Location:
Chr8:66697422-66706798 bp, + strand
Genetic Position: Chr8,
33.15 cM, cytoband B3-C2
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:47972
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Parent Cell Line:
| HM-1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd-Hprtb-m3
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaces most of the second exon encoding the fifth transmembrane domain and a part of the interrupting intron. (J:47972)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Npy1r Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:47972
Pedrazzini T et al.,
"Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor [see comments]"
Nat Med 1998 Jun;4(6):722-6
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All: |
12 reference(s)
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