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| Nomenclature |
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Symbol:
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Men1tm1.1Ctre
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Name:
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multiple endocrine neoplasia 1;
targeted mutation 1.1, Judy S Crabtree
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MGI ID: |
MGI:2158698 |
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Synonyms: |
Men1-, Men1deltaN3-8, Men1deltaN3-8 |
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Gene:
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Men1
Location:
Chr19:6334979-6340891 bp, + strand
Genetic Position: Chr19,
4.45 cM, cytoband A
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:67128
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Parent Cell Line:
| TC1/TC-1 (ES Cell) |
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Strain of Origin:
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129S6/SvEvTac
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: This allele is a derivative of Men1tm1Ctre in which the neomycin cassette and exons 3-8 of the gene were removed by Cre mediated recombination by crossing mice carrying the Mentm1Ctre allele to mice expressing Cre recombinase under the control of a ubiquitous promoter. (J:67128)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:67128
Crabtree JS et al.,
"A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors."
Proc Natl Acad Sci U S A 2001 Jan 30;98(3):1118-23
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All: |
9 reference(s)
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Analysis Tools
