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| Nomenclature |
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Symbol:
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Bmpr1atm1Bhr
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Name:
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bone morphogenetic protein receptor, type 1A;
targeted mutation 1, Richard R Behringer
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MGI ID: |
MGI:2158342 |
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Synonyms: |
Alk3null, Bmpr1a-, Bmpr-s |
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Gene:
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Bmpr1a
Location:
Chr14:34410734-34503341 bp, - strand
Genetic Position: Chr14,
20.81 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:30426
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A PGK-neomycin resistance cassette replaced 6.2 kb of sequence including the first two exons, which encode the translation initiation codon, the signal peptide, and ~30% of the extracellular domain. (J:30426)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:30426
Mishina Y et al.,
"Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis."
Genes Dev 1995 Dec 15;9(24):3027-37
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All: |
35 reference(s)
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Analysis Tools
