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| Nomenclature |
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Symbol:
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Foxj1tm1Slb
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Name:
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forkhead box J1;
targeted mutation 1, Steven L Brody
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MGI ID: |
MGI:2158221 |
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Synonyms: |
FoxJ1-, Foxj1lacZ, HFH-4 - |
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Gene:
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Foxj1
Location:
Chr11:116330704-116335399 bp, - strand
Genetic Position: Chr11,
81.16 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:73616
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Parent Cell Line:
| RW-4 (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: The gene was disrupted using neomycin resistance gene driven by a PGK promoter and fused with a lacZ gene. Insertion of the targeting cassette occurred in the first exon. Homozygous mutant animals did not express mRNA or protein as demonstrated by Northern and Western analysis. (J:73616)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Foxj1 Mutation:
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2 strains or lines available |
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Notes |
Phenotypic Similarity to Human Syndrome: Kartagener Syndrome or Primary Ciliary Dyskinesia (J:73616)
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| References |
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Original: |
J:73616
Brody SL et al.,
"Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice."
Am J Respir Cell Mol Biol 2000 Jul;23(1):45-51
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All: |
10 reference(s)
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Analysis Tools
