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| Nomenclature |
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Symbol:
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Twist1Pde
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Name:
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twist basic helix-loop-helix transcription factor 1;
polydactyly EMS
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MGI ID: |
MGI:2157489 |
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Synonyms: |
Pde, TwistJ |
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Gene:
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Twist1
Location:
Chr12:33957671-33959817 bp, + strand
Genetic Position: Chr12,
14.81 cM, cytoband B-C1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:60747
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Chemically induced (other) |
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Mutation: | |
Undefined |
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Mutation details: A complementation test confirmed that Pde is an allele of Twist. Sequencing the full-length cDNA and several hundred basepairs of genomic DNA upstream of the coding region failed to reveal a mutation, suggesting that the lesion may be in a regulatory element of the gene. (J:69450)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:60747
Munroe RJ et al.,
"Mouse mutants from chemically mutagenized embryonic stem cells."
Nat Genet 2000 Mar;24(3):318-21
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All: |
2 reference(s)
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Analysis Tools
