|
|
| Nomenclature |
|
Symbol:
|
Apobec1tm1Rub
|
|
Name:
|
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1;
targeted mutation 1, Edward M Rubin
|
|
MGI ID: |
MGI:2157378 |
|
Synonyms: |
Apobec-, apobec-1delta6 |
|
Gene:
|
Apobec1
Location:
Chr6:122577792-122602444 bp, - strand
Genetic Position: Chr6,
57.68 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:74021
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A genomic fragment containing exon 6 was replaced with a neomycin selection cassette. These sequences include the majority of the coding sequences of the gene. RT-PCR analysis confirmed the absence of encoded transcript in various tissues of homozygous mice. (J:74021)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:74021
Morrison JR et al.,
"Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism."
Proc Natl Acad Sci U S A 1996 Jul 9;93(14):7154-9
|
|
All: |
3 reference(s)
|
|
Analysis Tools
