|
|
| Nomenclature |
|
Symbol:
|
Pax63Neu
|
|
Name:
|
paired box gene 6;
3, Neuherberg
|
|
MGI ID: |
MGI:2156742 |
|
Synonyms: |
Enu-65, ENU-65 |
|
Gene:
|
Pax6
Location:
Chr2:105668896-105703160 bp, + strand
Genetic Position: Chr2,
55.31 cM
|
|
Mutation
origin |
|
Strain of Origin:
|
(102 x C3H)F1
|
|
Mutation
description |
|
Allele
Type: | |
Chemically induced (ENU) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: The mutation was identified as the insertion of single nucleotide (A) In exon 7 following Nucleotide 598. The frameshift results in normal protein through codon 145 of exon 7 followed by 12 aberrant amino acids and a premature stop codon. The linker region, homeodomain, and P/S/T domains are all deleted in the resulting protein. (J:73625)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
|
Notes |
Genbank Accession ID: Y19195
|
| References |
|
Original: |
J:21950
Favor J,
"A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea."
Mutat Res 1983 Aug;110(2):367-82
|
|
All: |
5 reference(s)
|
|
Analysis Tools
