|
|
| Nomenclature |
|
Symbol:
|
Amhr2tm1Bhr
|
|
Name:
|
anti-Mullerian hormone type 2 receptor;
targeted mutation 1, Richard R Behringer
|
|
MGI ID: |
MGI:2156555 |
|
Synonyms: |
Misr2- |
|
Gene:
|
Amhr2
Location:
Chr15:102445367-102454630 bp, + strand
Genetic Position: Chr15,
57.58 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:36027
|
|
Parent Cell Line:
| AB1 (ES Cell) |
|
Strain of Origin:
|
129S7/SvEvBrd-Hprt+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A 4.4 kb genomic fragment containing the first six exons was deleted and replaced with a neomycin selection cassette. RT-PCR analysis demonstrated that no transcript was detectable in the urogenital ridge of homozygous E13.5 embryos. (J:36027)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Amhr2 Mutation:
|
9 strains or lines available |
|
| References |
|
Original: |
J:36027
Mishina Y et al.,
"Genetic analysis of the Mullerian-inhibiting substance signal transduction pathway in mammalian sexual differentiation."
Genes Dev 1996 Oct 15;10(20):2577-87
|
|
All: |
4 reference(s)
|
|
Analysis Tools
