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| Nomenclature |
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Symbol:
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Smad1tm2Rob
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Name:
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SMAD family member 1;
targeted mutation 2, Elizabeth J Robertson
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MGI ID: |
MGI:2155484 |
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Synonyms: |
Smad1flox, Smad1RobPC |
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Gene:
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Smad1
Location:
Chr8:79338395-79399518 bp, - strand
Genetic Position: Chr8,
37.56 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:71998
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: An homologous recombination event inserted an EcoRI and loxP site 2kb 5' of the first coding exon, and a loxP-flanked hygromycin resistance cassette 1.7kb 3' of this exon.
(J:71998)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Smad1 Mutation:
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12 strains or lines available |
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| References |
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Original: |
J:71998
Tremblay KD et al.,
"Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation."
Development 2001 Sep;128(18):3609-21
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All: |
8 reference(s)
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Analysis Tools
