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| Nomenclature |
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Symbol:
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Pex5tm1Baes
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Name:
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peroxisomal biogenesis factor 5;
targeted mutation 1, Myriam Baes
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MGI ID: |
MGI:2154454 |
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Synonyms: |
Pex5- |
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Gene:
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Pex5
Location:
Chr6:124396817-124415067 bp, - strand
Genetic Position: Chr6,
59.15 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:42719
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Four exons encoding most of the tetratricopeptide repeats were replaced by a neo cassette. The absence of transcript was confirmed by Northern analysis and RT-PCR. By Western analysis, neither the 70kDa protein nor truncated forms were detectable from liver extracts. (J:42719)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pex5 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:42719
Baes M et al.,
"A mouse model for Zellweger syndrome."
Nat Genet 1997 Sep;17(1):49-57
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All: |
11 reference(s)
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Analysis Tools
