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| Nomenclature |
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Symbol:
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Tyrcm1OR
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Name:
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tyrosinase;
albino mottling 1, Oak Ridge
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MGI ID: |
MGI:2153728 |
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Synonyms: |
cm1OR, Tyrc-1R |
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Gene:
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Tyr
Location:
Chr7:87427405-87493411 bp, - strand
Genetic Position: Chr7,
49.01 cM
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Transposon insertion |
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Mutation details: The mutation is a 5.4kb intracisternal A particle (IAP) element insertion upstream of the promoter. This is a hypomorphic allele; Northern blot analysis and RT-PCR results show that expression is at much lower levels in homozygous than in wild-type mice.(J:38209)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:38209
Wu M et al.,
"Inherited somatic mosaicism caused by an intracisternal A particle insertion in the mouse tyrosinase gene."
Proc Natl Acad Sci U S A 1997 Feb 4;94(3):890-4
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All: |
1 reference(s)
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Analysis Tools
