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| Nomenclature |
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Symbol:
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Msh2tm1Rak
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Name:
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mutS homolog 2 (E. coli);
targeted mutation 1, Raju Kucherlapati
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MGI ID: |
MGI:2151801 |
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Synonyms: |
Msh2deltaN7 |
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Gene:
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Msh2
Location:
Chr17:87672330-87723713 bp, + strand
Genetic Position: Chr17,
57.87 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:64667
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: Exon 7 was replaced with a vector, inserted in reverse orientation, containing the neomycin resistance gene. (J:64667)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:64667
Smits R et al.,
"Somatic apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity"
Genes Chromosomes Cancer 2000 Nov;29(3):229-39
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All: |
12 reference(s)
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Analysis Tools
