|
|
| Nomenclature |
|
Symbol:
|
Hoxa1tm3.1Mrc
|
|
Name:
|
homeobox A1;
targeted mutation 3.1, Mario R Capecchi
|
|
MGI ID: |
MGI:2151686 |
|
Synonyms: |
Hoxa1GFPlox |
|
Gene:
|
Hoxa1
Location:
Chr6:52155367-52158317 bp, - strand
Genetic Position: Chr6,
25.4 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:50569
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: Insertion of a eGFP gene in-frame to sequences encoding the Hoxa1 gene. An adjacent loxP-flanked neomycin cassette was removed via Cre-mediated recombination in mice in this derivative of Hoxa1tm3Mrc. A Hoxa1-eGFP fusion protein is expressed from this allele in a pattern identical to that predicted by in situ hybridization analysis. (J:50569)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Hoxa1 Mutation:
|
6 strains or lines available |
|
| References |
|
Original: |
J:50569
Godwin AR et al.,
"Detection of targeted GFP-Hox gene fusions during mouse embryogenesis."
Proc Natl Acad Sci U S A 1998 Oct 27;95(22):13042-7
|
|
All: |
5 reference(s)
|
|
Analysis Tools
