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| Nomenclature |
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Symbol:
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Fgfr1tm1Led
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Name:
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fibroblast growth factor receptor 1;
targeted mutation 1, Philip Leder
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MGI ID: |
MGI:2150650 |
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Synonyms: |
Fgfr-1ex4 |
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Gene:
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Fgfr1
Location:
Chr8:25513654-25575714 bp, + strand
Genetic Position: Chr8,
14.12 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:22118
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin cassette disrupted exon 4 of the gene, introducing stop codons in the three reading frames and truncating the coding sequence immediately after the Ig2 domain. (J:22118)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:22118
Deng CX et al.,
"Murine FGFR-1 is required for early postimplantation growth and axial organization."
Genes Dev 1994 Dec 15;8(24):3045-57
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All: |
3 reference(s)
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Analysis Tools
