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| Nomenclature |
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Symbol:
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Eya1tm1Rilm
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Name:
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eyes absent 1 homolog (Drosophila);
targeted mutation 1, Richard Maas
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MGI ID: |
MGI:2150426 |
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Synonyms: |
Eya1- |
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Gene:
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Eya1
Location:
Chr1:14168958-14310199 bp, - strand
Genetic Position: Chr1,
4.31 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:57313
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A neomycin cassette replaced exons 10-13, encoding 153 residues of the Eya domain. (J:57313)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:57313
Xu PX et al.,
"Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia."
Nat Genet 1999 Sep;23(1):113-7
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All: |
20 reference(s)
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Analysis Tools
