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| Nomenclature |
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Symbol:
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Hes5tm1Fgu
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Name:
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hairy and enhancer of split 5 (Drosophila);
targeted mutation 1, Francois Guillemot
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MGI ID: |
MGI:2149674 |
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Synonyms: |
Hes5- |
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Gene:
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Hes5
Location:
Chr4:154960923-154962371 bp, + strand
Genetic Position: Chr4,
86.01 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:54662
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK-neomycin resistance cassette replaced 724 bp of sequence including the region that encodes the bHLH domain (Met1 to Ala76). (J:62024)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hes5 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:54662
Ohtsuka T et al.,
"Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation."
EMBO J 1999 Apr 15;18(8):2196-207
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All: |
23 reference(s)
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Analysis Tools
