|
|
| Nomenclature |
|
Symbol:
|
Irs3tm1Lhd
|
|
Name:
|
insulin receptor substrate 3;
targeted mutation 1, Gustav E Lienhard
|
|
MGI ID: |
MGI:2149647 |
|
Synonyms: |
IRS-3-, IRS3- |
|
Gene:
|
Irs3
Location:
Chr5:137643032-137645714 bp, - strand
Genetic Position: Chr5,
76.59 cM, cytoband G2
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:55667
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
A neomycin resistance cassette disrupted the coding region of the gene. (J:55667)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:55667
Liu SC et al.,
"Insulin receptor substrate 3 is not essential for growth or glucose homeostasis."
J Biol Chem 1999 Jun 18;274(25):18093-9
|
|
All: |
4 reference(s)
|
|