|
|
| Nomenclature |
|
Symbol:
|
Insl3tm1Par
|
|
Name:
|
insulin-like 3;
targeted mutation 1, Luis F Parada
|
|
MGI ID: |
MGI:2148889 |
|
Synonyms: |
Insl3- |
|
Gene:
|
Insl3
Location:
Chr8:71689214-71690575 bp, + strand
Genetic Position: Chr8,
34.43 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:55881
|
|
Parent Cell Line:
| R1 (ES Cell) |
|
Strain of Origin:
|
(129X1/SvJ x 129S1/Sv)F1-Kitl+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: An IRES-lacZ-PGK-neomycin resistance cassette replaced a 1190 bp region containing the complete coding sequence for the gene. In situ studies of testis did not detect Insl3 expression in Leydig cells from homozygous mutant mice. Expression of the inserted lacZ gene was not reported. (J:55881)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Insl3 Mutation:
|
1 strain or line available |
|
| References |
|
Original: |
J:55881
Nef S et al.,
"Cryptorchidism in mice mutant for Insl3."
Nat Genet 1999 Jul;22(3):295-9
|
|
All: |
3 reference(s)
|
|
Analysis Tools
