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| Nomenclature |
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Symbol:
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Utrntm1Ked
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Name:
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utrophin;
targeted mutation 1, Kay E Davies
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MGI ID: |
MGI:2148589 |
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Gene:
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Utrn
Location:
Chr10:12382188-12861735 bp, - strand
Genetic Position: Chr10,
3.77 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:70949
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: Insertion of a neomycin cassette into exon 7. No protein was detected in extracts derived from kidney, lung or brain of homozygous mice as assayed by Western blot analysis. (J:70949)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:70949
Deconinck AE et al.,
"Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice."
J Cell Biol 1997 Feb 24;136(4):883-94
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All: |
25 reference(s)
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Analysis Tools
