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| Nomenclature |
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Symbol:
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Ctnnb1tm2.1Kem
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Name:
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catenin (cadherin associated protein), beta 1;
targeted mutation 2.1 Rolf Kemler
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MGI ID: |
MGI:2148569 |
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Synonyms: |
beta-catenindel, Ctnnb1Del, floxdel |
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Gene:
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Ctnnb1
Location:
Chr9:120929216-120960507 bp, + strand
Genetic Position: Chr9,
72.19 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:67966
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: This allele is a derivative of Catnbtm2Kem in which Cre mediated recombination removed exons 2 through 6. (J:67966)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ctnnb1 Mutation:
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12 strains or lines available |
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| References |
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Original: |
J:67966
Brault V et al.,
"Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development."
Development 2001 Apr;128(8):1253-64
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All: |
31 reference(s)
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Analysis Tools
