|
|
| Nomenclature |
|
Symbol:
|
Neurod1tm1Mjts
|
|
Name:
|
neurogenic differentiation 1;
targeted mutation 1, Ming-Jer Tsai
|
|
MGI ID: |
MGI:2148229 |
|
Synonyms: |
BETA2- |
|
Gene:
|
Neurod1
Location:
Chr2:79452521-79456751 bp, - strand
Genetic Position: Chr2,
47.58 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:43010
|
|
Parent Cell Line:
| AB2.2 (ES Cell) |
|
Strain of Origin:
|
129S7/SvEvBrd-Hprtb-m2
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A PGK-neomycin cassette replaced all but the first 66 amino acids of the gene, deleting sequences encoding the basic helix-loop-helix (bHLH) and transactivation domains. (J:43010)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Neurod1 Mutation:
|
3 strains or lines available |
|
| References |
|
Original: |
J:43010
Naya FJ et al.,
"Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice."
Genes Dev 1997 Sep 15;11(18):2323-34
|
|
All: |
16 reference(s)
|
|
Analysis Tools
