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| Nomenclature |
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Symbol:
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Tg(Pcp2-cre)2Mpin
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Name:
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transgene insertion 2, Max-Planck-Institute of Neurobiology
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MGI ID: |
MGI:2137515 |
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Synonyms: |
L7-cre, L7Cre-2, pcp2Cre-2 |
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Transgene:
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Tg(Pcp2-cre)2Mpin
Location:
unknown
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Show the 1 image(s) involving this allele.
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Transgene
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:66884
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: These transgenic mice express Cre recombinase under the direction of the Purkinje cell-specific L7/Pcp2 promoter. Recombinase activity is observed in most Purkinje cells and some retinal bipolar neurons. Small amounts of activity are observed in an unidentified population of cells of the central nervous system tissue. Recombination is first observed around postnatal day 6 and is fully established 2 to 3 weeks after birth. (J:66884)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:66884
Barski JJ et al.,
"Cre recombinase expression in cerebellar purkinje cells"
Genesis 2000 Nov-Dec;28(3-4):93-8
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All: |
51 reference(s)
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Analysis Tools
